WebMedscape - Indication-specific dosing for Afinitor, Zortress (everolimus), frequency-based adverse effects, comprehensive interactions, contraindications, pregnancy & lactation schedules, and cost information. ... Brand and Other Names: Afinitor, Zortress, more ... Prescribing information for coadministration with cyclosporine (a CYP3A4 and P ... WebJun 7, 2024 · At the molecular level, everolimus forms a complex with the cytoplasmic protein FKBP-12. In the presence of everolimus, the growth factor-stimulated phosphorylation of the p70 S6 kinase is inhibited. Since p70 S6 kinase phosphorylation is under the control of FRAP (also called m-TOR), this finding suggests that the …
Afinitor: Side Effects, Cost, Uses, and More - Healthline
WebThe brand names mentioned in this document are the property of their respective trademark owners. Approved Use AFINITOR ® (everolimus) Tablets is a prescription medicine used to treat adults with advanced kidney cancer (renal cell carcinoma or RCC) when certain other medicines (ie, Sutent ® [sunitinib] or Nexavar ® [sorafenib]) have not … Webeverolimus systemic. Brand names: Afinitor, Afinitor Disperz, Zortress. Drug classes: mTOR inhibitors, selective immunosuppressants. Everolimus systemic is used in the treatment of: Brain Tumor. Breast Cancer. … kitchenaid kmbd104gss specs pdf
Certican Uses, Dosage, Side Effects, FAQ - MedicinesFAQ
WebBrand Names. Afinitor, Votubia, Zortress. Generic Name Everolimus DrugBank Accession Number DB01590 Background. Everolimus is a derivative of Rapamycin (sirolimus), and works similarly to Rapamycin as … WebDec 30, 2024 · Afinitor is a brand-name medication that contains the active drug everolimus. This active drug is also available as a generic medication. A generic drug is … Everolimus, sold under the brand name Afinitor among others, is a medication used as an immunosuppressant to prevent rejection of organ transplants and as a targeted therapy in the treatment of renal cell cancer and other tumours. It is the 40-O-(2-hydroxyethyl) derivative of sirolimus and works similarly to sirolimus as an inhibitor of mammalian target of rapamycin (mTOR). kitchenaid kmbd104gss microwave drawer