WebG28UCM-treated tumours showed apoptosis and inactivation of HER2, ERK1/2 and mTOR signalling pathways, without affecting FASN protein expression levels. This figure only shows a representative animal of each experimental group (4C -control-, 4T -treated no-responsive- and 12T -responsive-). Chromogenic in situ hybridization (CISH) is a cytogenetic technique that combines the chromogenic signal detection method of immunohistochemistry (IHC) techniques with in situ hybridization. It was developed around the year 2000 as an alternative to fluorescence in situ hybridization (FISH) for detection of HER-2/neu oncogene amplification. CISH is similar to FISH in that they are both in situ hybridization techniques used to detect the presence or absence of sp…
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WebOct 6, 2024 · What is HER2? The human epidermal growth factor receptor 2 (HER2) gene is responsible for producing HER2 proteins. HER2 proteins are present on the surface of some breast cancer cells. When... WebChromogenic in situ hybridization (CISH) testing is sensitive and specific in detecting HER-2/neu gene amplification. Direct evaluation of gene amplification using CISH assay is a reliable... how does whole foods treat their employees
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WebJun 16, 2024 · Bond Oracle HER2 IHC System (Leica Biosystems) Breast Cancer - Tissue Herceptin (trastuzumab) BLA 103792 ERBB2 (HER2) HER-2 protein overexpression ... Dako c-KIT pharmDx (Dako North America, Inc ... Web· Established experience with Breast Pathology and Digital Imaging Analysis for ER, PR, HER2, ki67; along with, single probe HER2 CISH and dual probe HER2 ISH for quantitative & qualitative ... WebOct 1, 2007 · CISH analysis of HER2 amplification was performed with the SPoT-Light assay in accordance with the manufacturer's protocol. The DNA probe (HER2 SPoT-Light) and sections were denatured at 94 to 95°C and hybridised overnight at 37°C with a … photographers va beach