WebOct 23, 2013 · Efficacy and Safety of Diclofenac DDEA 2.32 % in Patient Suffering From Knee Osteoarthritis (OA) ... Novartis: ClinicalTrials.gov Identifier: NCT01967550 Other Study ID Numbers: 194-P-308 2012-004024-38 ( EudraCT Number ) First Posted: October 23, 2013 Key Record Dates: Results First Posted: ... WebMay 17, 2024 · INTRODUCTION. Total knee replacement, also known as total knee arthroplasty, is a surgical procedure in which parts of the knee joint are replaced with artificial (prosthetic) parts ().A normal knee functions as a hinge joint between the upper leg bone (femur) and the lower leg bones (tibia and fibula) ().The surfaces where these bones …
LNA043, a Novel Cartilage Regenerative Treatment for …
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Angiopoietin-like 3-derivative LNA043 for cartilage
WebSep 3, 2024 · Novartis (NYSE:NVS) has received FDA fast track designation for LNA043, a potential treatment for osteoarthritis of the knee. LNA043 is a modified version of the human angiopoietin-like 3 (ANGPTL3). The drug would be a potential first-in-class disease-modifying osteoarthritis therapy. Osteoarthritis is a common joint disorder. WebNov 10, 2024 · Originator Novartis Class Antirheumatics Mechanism of Action Undefined mechanism Orphan Drug Status No New Molecular Entity Yes Highest Development Phases Phase II Osteoarthritis Most Recent Events 28 Sep 2024 LRX 712 is still in phase II trials for knee osteoarthritis in Netherlands and Austria WebNov 18, 2024 · Osteoarthritis is an autoimmune disease that causes swelling and stiffness in the joints of the feet and hands. It is considered to be a normal part of aging and often starts in middle age... fluid head for photography