Proved digoxin trial
WebbA post hoc analysis of the DIG trial demonstrated that discontinuation of digoxin is associated with poor outcomes in ambulatory patients with chronic HFrEF (13). Patients … Webb27 jan. 2014 · In the Digitalis Investigation Group (DIG) trial, the largest randomized clinical trial (RCT) of digoxin efficacy in heart failure (HF), digoxin reduced the combined …
Proved digoxin trial
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Webb1 jan. 2024 · In a recently published post hoc analysis of the ARISTOTLE trial, the risk of death was independently related to the digoxin serum concentration in AF patients. 8 Each 0.5 ng/ml increase in baseline serum digoxin concentration was associated with an increase in death (adjusted HR 1.19, 1.07 to 1.32), which was consistently observed in … Webb8 dec. 2005 · Abstract. Aims To determine the effects of digoxin on all-cause mortality and heart failure (HF) hospitalizations, regardless of ejection fraction, accounting for serum digoxin concentration (SDC).. Methods and results This comprehensive post-hoc analysis of the randomized controlled Digitalis Investigation Group trial (n=7788) focuses on …
Webbplacebo-controlled digoxin trial (PROVED) (1). He questions the scientific validity of a drug withdrawal design . Such a design was necessitated by the nearly universal use of digoxin in the treatment of heart failure in this country at the time that this study was promulgated. A limitation of this design, not mentioned by Dr. Webb11 juli 2013 · In the DIG trial, digoxin had a profound impact on hospitalization due to worsening heart failure. Digoxin also significantly reduced the rate of all-cause hospitalizations during the mean 37-month follow-up period, but this effect was modest (8% relative reduction).
Webb20 feb. 1997 · Background: We studied the effect of digoxin on mortality and hospitalization in a randomized, double-blind clinical trial. Methods: In an ancillary trial of patients with ejection fractions greater than 0.45, 492 patients were randomly assigned to digoxin and 496 to placebo. Results: Webb1 okt. 1993 · Withdrawal of digoxin (placebo group, n = 46) or its continuation (digoxin group, n = 42) was performed in a prospective, randomized, double-blind, placebo …
WebbBackground Although digoxin is effective in the treatment of patients with chronic heart failure who are receiving diuretic agents, it is not clear whether the drug has a role when …
Webb1 juli 1994 · A controlled trial of digoxin in congestive heart failure. Am J Cardiol, 61 (1988), pp. 371-375. Article. Download PDF View Record in Scopus Google Scholar. 21. Haerer W, Bauer U, Hetzel M, Fehske J. ... Results of the PROVED trial. J Am Coll Cardiol, 22 (1993), pp. 955-962. Article. peterman\u0027s bowls french king highwaypeterman\u0027s boards \u0026 bowls incWebb20 mars 2024 · In the DIG trial, about 44% of patients received digoxin before randomization and were treated in a randomized withdrawal design, whereas 56% of … starlite recovery center kerrvilleWebb30 maj 2006 · Digoxin was added in only 8% of patients before discharge despite the fact that they had signs and symptoms of heart failure while receiving diuretics, ACE … starlite recovery center llcWebbRandomized study assessing the effect of digoxin withdrawal in patients with mild to moderate chronic congestive heart failure：results of the PROVED trial.PROVED Investigative Group [J]． J Am Coll Cardiol ， 1993 ， 22 (4): 955-962. peterman\u0027s clothingWebb1 apr. 1997 · The long awaited results of the digoxin trial, reported at the American Heart Association meeting in November 1996, have now been published. This large trial … starlite recovery center fax numberWebbIn recent trials, digoxin has been shown to reduce morbidity associated with congestive heart failure but to have no demonstrable effect on survival. starlite recovery center jobs